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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6425d0dd5fe5f3cff5a820f85ef80e18ea37d10ad159502d2239b16245030993' 
  AND token = 'ClXEhjGdJGpG5qgx1Jim4hrCobQmE+RSM2t8L9ws7iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}