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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5cf64e43e003f16b2bda78e44c4823609134e9aa9eef6a07316177585d6274a' 
  AND token = 'qDdo3S9ao5fsTcniK7FSQRRtXjLH73CN2rrOUC2HLLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}