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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82d8a638d1f0d4b58ec296e0212bab320f816586139693f3fa2fb6d13ecaf17e' 
  AND token = 'cp9kNb/TXF/MYVaNojkQ8gVbDa2XmAvvp0tMD6ycb6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}