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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e0b8d5c9a40231cb5951a763537ac13b24eed943530dc3b127b70bf7508aca' 
  AND token = '5RBmkFTxjGJEHEeFaeFPqRiJXAcCW7fj4Tw/W8zT2sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}