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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9273bfae2c34a58988992f61a1d6988b2e53d691b990e847cfbc9118c671dcae' 
  AND token = 'f0HsHcay0IbchlEiBM/cEEnkYxpp74Wq2LUcB3OzB9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}