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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21cae992a04c5a5e0ee8e11fdd92e21a8f3c75a072e77f00f5a333084817af24' 
  AND token = 'AEN/KkY7J23ehHw4Sz6tL/pnrZG+nqMTuAz5xn/DbzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}