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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59b01f5ba3415f2ac7a665d9b2b88ac3a90ab03ac11013a804bce4ab7af24952' 
  AND token = '8EyNKT9LKAFkWPBoTofPLhNwvzHTqch1d5ui4++4dPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}