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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec207abc09a8bd658df0e66ddfca86bbebf38953044844eca3345b6b457f48c1' 
  AND token = 'okXTNf8Sfy5wRawL8HihdwgHuCug1dKuk+9+oh3eWlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}