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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05e867353ad7dc05cadee421cf775680a04d0d90e8170ea980e1514565db01b' 
  AND token = 'idt96I4ckdqCw/4Zh95XyD72TwGZWeWHUro+xCNiIEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}