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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e39ce8bb5c0cf2d714c1abbb058ee7252807efb91bec356ba1dbe3354bd4d9c' 
  AND token = '8tQN2MgR4lTsPRHrhLvWrOmRys6mQ00b5lBqzsleGQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}