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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550a3081e30d99644b14b1baeba78e4ae4588315ce09358fb262c60b311fe809' 
  AND token = 'C2V9KgRZ0xaUQEJqH0GTE4RdIt/GVf1bjT0wuVsqAF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}