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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e81c8cf7ab4d58d7cf04dddc389aa030262c40e402ec801d59d423a35f1f110' 
  AND token = 'aRrRgg2zX6iQy6Bzbtr2JTa8YNdhim5mCGqWhn/PUYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}