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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a887a78ed3f2b4d931ea5dd149ac6cd46a45830682b91816a284c485bd2afb' 
  AND token = 'HykRG5whtwuwBJYOci/m9M/O9dQQzMS5x31Zsnhly44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}