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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c913a294f586c9a553e77c826fa574f06f220fff8108ef0ff3b88515759e34c8' 
  AND token = 'S/A32MSi/Ui1x7xhhLlv9kQlw0QZFnTOIG1t8oCtuAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}