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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33376b3852e4fc9f943be6cf0fe50e26a5bad7b27631ff0c8a91474da6d1669a' 
  AND token = 'xUDhfLZaVRedqJzw0cN4qxEZtAlLa58M5XJtXHiXuxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}