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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c252891ff1fdf4024c3e7e60dcd7fb1b51ea29024e3d4b71f719a16c02ea3fe4' 
  AND token = '2xb7TWh0QUtg8hFXOHCw9Lu+Bc+tAYi93uAriFvGa2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}