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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fedee763f28e733561326facfcf0cf216378a6d90ef118a0b7a0b77ae603262' 
  AND token = 'zmAW/ySkJq5/0zCL0QMbwRZ1hUYrFeOTUA8DuNklfnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}