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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ecc660a19c1d910a094c0c6396b06d9e1b8290b2de6848a0fd7159a8209d40' 
  AND token = '3at8+ReXqkYVCNRBQ7c/PUMITechHtU1ESdnjT1SJMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}