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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc582fc4b4e53a98c5d876621a30f67c2d658ad974c9b7143445d0aa1d87881' 
  AND token = 'S4fc+rGP2vA4issEwMS9peR/2uHetuEFtN5bYQYowDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}