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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c3f2969b29a18daa7529bbfae7ca71e3f702c8e9e3f9f21afa7632d7c231e3' 
  AND token = 'wfS4i8cheI3x5PnmrmG4dL8Fju9uMuXjbyv+lNo5xXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}