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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2657c7203814d4f2ab3b8a6f57a8721a3e58188dfa8e60e9c81b3d0cc567872f' 
  AND token = 'OQK7Rg5wBghy69ZeOGQa/sRxhF9IZb6EZ94G2bI0pgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}