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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '439d69c72dc00282b37fe47395b015d0455051dd8c637b29ebfe42fbcacfc6af' 
  AND token = 'B3VqwhV9Mssr0/pZDDzkqza5TaT3sUUjdUhG0skd/dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}