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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6efd988e0fbfa5ccfa270f31d908f45b67c48f9cf6a5a4e2396136daf575dc87' 
  AND token = '95Zr0c/9O+xMYGDcJUZOefBVM+a46b8w7spp7bHyUMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}