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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb5432f1dad198fa222306d6260cc5c29b9a3d6d85af2dffd154dfb2eaa334da' 
  AND token = 'iMSxfYDQUhxyMflASR1qIgQyTNljTwby711QheRDlOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}