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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '955dfff0d9e51692737cfbd2c75b5479c1cc2c1003b785e7c7944022b18006c3' 
  AND token = 'EZnuzeQOYi6YPtbO7JfyCMNi9K8DgSp98pOGMskoj5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}