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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00425c46cf4adc8b340c6351ffd787c9573fb407ec87cd8dbe54ecf50d8e1274' 
  AND token = 'JpMmC1+yQGWAlY0WxOfs4XHV4HDuTflfTErmdpijtPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}