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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '081ff4b4af466740072a83739d0f727467ccd1578886f46e8a89b03aaa2220a0' 
  AND token = 'AN/j7ujVBhCjULlPr6TwQFb2rTv18mAM1TlVBuCVWs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}