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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe03c4c8da14ebc2b95b85846b99d12ad850a6d9a6b449a229b1f80c9d911450' 
  AND token = 'j/zHJJtamYi32e/DQfqjDEcT6vGFCbTCQCb+k8fE1S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}