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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e67e7e8a2d0c49528e41bd8e967ccc8800f0ede3181e1fb71afc006988711f' 
  AND token = 'fxarIDztw+TA81wSFsz8ZrlIswBM3fvsOKBHZqYKy+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}