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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d4e26f6c5e981d3fd400c8524c4ad4eb996da7bae61847b8bb0bc3d148e3ff' 
  AND token = 'YVWvkQkQCjrOWJf/mbkhZAsQDGaE6mC7Ddm07WPTLPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}