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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6d0eb744023001de5a7d51ddb8be223696282e2e7fd95461e4bda8043a2c6a7' 
  AND token = 'cweEQN1pcA5uUl93H4ZW6z9edSZFwxuopxZiW0LHQQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}