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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e02085358bcafc1997c1d7147d0e2b9595cb4909409a4d90aea21b132bd6e1' 
  AND token = '4c2ydEVYRUmJKQBKhRhI4O3MvCqjrSqvFV3070/Ynt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}