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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686e59b43e8dafa90d19611d636d86efbafb7e64c8e7e952a0b6cba42e264d7f' 
  AND token = 'wW+qmFGRPFlS/+8V6IyITPCDwyqpO2nZ0h0Rqm4xb9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}