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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9622f34d80f2b023c75cf57a2964bbd69be17ee0a579d83e22b898f4121057c' 
  AND token = 'PbrDuZannMOSTyrsMNgjT9s6DvEHmTrg2XbBqyCTHZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}