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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '671b8a20ee8f1b7d6b6206348195b42aa50a30b2c78efe7c7e5327f803b6bef3' 
  AND token = 'Nj24uEJ3GL6xDAQKoJhbHlNVfKpDUTsDSlq/N5beqLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}