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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887cfb5225afd10ee9936697c867b1fb3589bdce5457ab316dc5273f29af2976' 
  AND token = 'y0DdJtY6dATUeWfBi0ihCNf/89IMiExugNeIs/mVlyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}