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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34475eb321a3dda93d1beb9796805bfa7da7d01382d6eef411b7fa0550818e45' 
  AND token = '+twd251lK9OaJOIuEIDsK0BbszHtOyjCYJ9zX1WUndw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}