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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2942dd5cf287525dc31124650074401e2aec150e78f02367681f11f03eb6bac1' 
  AND token = 'O3w+RGaWEhKcIFXbt9G+MCaxupB4EuDfwLaSDgAqb5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}