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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e40f52f2cc77091b14575207cb0ffb12547ff3cf77cc639c174b2f755b5495f' 
  AND token = 'a+12ACBzIM+NPhgRsU91VkunauBxXwupj4DidkbtZk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}