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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f970e7f8c231c74f09649961f178c933fe9a703b690a65f2a3a100b8722eeed9' 
  AND token = 'BbSdiAhJTgz7RgUgKuJx4DeFh7h3b98CAOvzw+Z76bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}