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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3943c2fce58edabec9cb58cec93ad4ee740187ed65388282b055d7f320008a90' 
  AND token = '0eWZCUgX2iW872MkY6ygHHW5+sE0sVlbflJJB/I3k6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}