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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8f1bfee7cdc72a0f40a0b289df677b7313ac4ad08ea287b75171cc103ee78a' 
  AND token = '6oysh22yvjZNdMWulDIhws4pS9anmyV71JOTW1XltZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}