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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006453ea7ec18c7f47df0cd007a8c86e7a4d6164aeea9ed81b4c15f424052638' 
  AND token = 'mkhW044zl+nZlhrpkFv1JT6tXxHgCt20lSQQJRjU/g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}