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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd06d58a968bd301a4b43d539526c29e49a3153d27b9166689852c3d0570b4d7f' 
  AND token = 'PUf4PitiesX3N8DNdaPSHQyVLIrY9u7bUdBjfnrdkVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}