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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf2438924eb587d392966feca059ce09a710816abe47d8af8fb56b5a680a4dbd' 
  AND token = '+XlDgCd7fW7PXX+3pl3H8/oSs6sP7lOCH6OxjGXfOpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}