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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d1c581455b0800bc49d32db827555ff9f2f52fffe7d170ff8880323acdf25f1' 
  AND token = 'TUE8wdQC/l+pJBsFJRpmI7w33K8A2oOBwQTTBHZmkOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}