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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b901a999357d7fd1fd3a303c40edba1bad2fe6d07e4bc5f145493bff1d9f74d4' 
  AND token = 'ztHSy7xkEOQUGul7pepUTdw3LnG0kviFFNHtNyRt24U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}