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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e70675ba11ecf2bfc590118bae7d2c8fb95e8055040f0c29da98e4a00baff47b' 
  AND token = 'sNh33WX+DBEO4JNEZVvzWyj4Fmqf6W+9NEYpT21U210=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}