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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe1cb0d98362a56cc622bc3a9316d2d61cf619dfceaaf8f4f595138e35035f1a' 
  AND token = 'knAmhlUR57wiF47Tz3zC9xTyfveTXW8yAmZC4J+9CYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}