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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9edc6fa23466ffbc44239552bd1ac0d03151ee4c83caa90bf3a5155f5207f2fb' 
  AND token = 'y5fDqx2/tUQ4dwSwLUGPacvLNZD9MN2PkKt1xVsTrhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}